Volume 6, Issue 3, September 2018, Page: 37-43
Models of Distribution of Electric Field of Primary Cilia as Monopole Antennas
Josef Dvorak, Department of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic
Bohuslav Melichar, Department of Oncology, Palacky University Medical School and Teaching Hospital, Olomouc, Czech Republic
Alzbeta Filipova, Department of Radiobiology, Faculty of Military Health Sciences in Hradec Kralove, University of Defense in Brno, Hradec Kralove, Czech Republic
Tomas Korinek, Department of Electromagnetic Field, Faculty of Electrical Engineering, Czech Technical University, Prague, Czech Republic
Nela Grimova, Department of Cybernetics, Faculty of Electrical Engineering, Czech Technical University, Prague, Czech Republic
Jana Grimova, Medicon, Prague, Czech Republic
Aneta Rozsypalova, Department of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic
Jan Proks, Department of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic
Tomas Buchler, Department of Oncology, First Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic
Igor Richter, Department of Oncology, Regional Hospital, Liberec, Czech Republic
Received: Aug. 19, 2018;       Accepted: Oct. 11, 2018;       Published: Nov. 7, 2018
DOI: 10.11648/j.jctr.20180603.11      View  98      Downloads  8
Abstract
Background: The primary cilium is a solitary, chemosensory and mechanosensory, non-motile microtubule-based organelle which in the quiescent cell cycle phase projects from the surface of most cells in vertebrates, including humans. A hypothesis has been proposed that the cell endogenous electromagnetic field results from a unique cooperating system among microtubules and mitochondria. The present study expands this prior hypothesis of the endogenous electromagnetic field in the cell to the present hypothesis that primary cilium could serve as a monopole antenna. It is proposed that primary cilia as monopole antennas can serve for both transmitting and receiving signals at the same frequency. Results: There was simulated the distribution of electric field of primary cilium as a monopole antenna of a single cell, primary cilia after mitosis and primary cilium of renal tubule in water environment. According to simulations of the distribution of electric field of primary cilium as a monopole antenna, the electromagnetic waves radiate not only to the neighbouring cells, but also to the nucleus of the cell proper where the gene expression during the cell cycle could be changed. Conclusions: The present study provides the first simulations of electromagnetic field of primary cilia as monopole antennas. The proof of this function of primary cilia could extend diagnostic and therapeutic modalities. There are several ways to verify this hypothesis. For example, it is possible to use the voltage sensitive dyes in the microenvironment outside the primary cilium or photon counting with low noise and highly sensitive photon counting system.
Keywords
Primary Cilia, Monopole Antennas, Distribution of Electric Field Models
To cite this article
Josef Dvorak, Bohuslav Melichar, Alzbeta Filipova, Tomas Korinek, Nela Grimova, Jana Grimova, Aneta Rozsypalova, Jan Proks, Tomas Buchler, Igor Richter, Models of Distribution of Electric Field of Primary Cilia as Monopole Antennas, Journal of Cancer Treatment and Research. Vol. 6, No. 3, 2018, pp. 37-43. doi: 10.11648/j.jctr.20180603.11
Copyright
Copyright © 2018 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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